Downregulated def
Webdown·reg·u·la·tion. ( down-reg-yū-lā'shŭn) Development of a refractory or tolerant state consequent on repeated administration of a pharmacologically or physiologically active … WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
Downregulated def
Did you know?
WebMar 29, 2024 · Downregulation: An decrease in the number of receptors on the surface of target cells, making the cells less sensitive to a hormone or another agent. For example, … Webdownregulation (redirected from Downregulate) Also found in: Medical. Related to Downregulate: Upregulate downregulation ( ˌdaʊnrɛɡjʊˈleɪʃən) n (Medicine) a decrease in sensitivity, through overexposure, to a drug or other chemical caused by a reduction in the number or density of receptors on cell surfaces
WebDownregulation • Downregulation specifically refers to a reduction in the total number of receptors available to be stimulated due to prolonged receptor activation (e.g. by chronic treatment with a pharmacological agonist drug or prolonged inhibition of metabolism of a neurotransmitter). Webdownregulate (down-rĕg′ū-lāt″) To inhibit or suppress the normal response of an organ or system (e.g., the immune system or the central nervous system). Medical Dictionary, © …
WebSep 8, 2024 · Genes are encoded by DNA, which can be subject to upregulation and downregulation in terms of being transcribed to a messenger RNA (mRNA) and then … WebApr 9, 2024 · Definition of 'downregulate' downregulate noun to decrease the sensitivity to a drug or other chemical by reducing the number or density of receptors on cell surfaces …
WebNov 8, 2024 · The standard definition of the fold-change for gene i is (e.g. Tusher et al. 2001) F Ci = x 0 i· /y 0 i· (2.3) where x 0 ij and y 0 ij are the raw expression levels of gene i in replicate j in ...
WebInsulin resistance is a complex condition in which your body does not respond as it should to insulin, a hormone your pancreas makes that’s essential for regulating blood sugar levels. Several genetic and lifestyle factors can contribute to insulin resistance. Symptoms and Causes Diagnosis and Tests Management and Treatment Prevention sunknowledge 2021WebReceptor downregulation is characterized by a decrease in total receptor number in the cell due to endocytosis and subsequent degradation of the receptors caused by long-term … sunklands conservation area moWebBoth up- and downregulation of HR have been described in oncogenic situations, highlighting the necessity for a precise equilibrium in HR regulation. Indeed, both decreased and increased HR can generate genetic instability (see earlier). sunkist water flavor packetsWebWhat's the definition of Down-regulate in thesaurus? Most related words/phrases with sentence examples define Down-regulate meaning and usage. sunkne meadow restorationWebMar 16, 2024 · From the very small set of conserved genes (Fig. 2, dark green outline, 29 up, 30 down, Supplementary Table 3) we could identify 7 enriched functions or pathways, of which 6 involve downregulated genes and only 1 upregulated gene (Fig. 3 A, Supplementary Table 4). All downregulated 6 functions are related based on the … sunknowledge logoWebIL-2 and TLR-7 were elevated from the beginning of the infection in both CEF and DEF to the end of the experiment. Chicken MHC class I expression was almost unaffected while … sunkni iatable tummy time water play matWebNov 3, 2024 · downregulate ( third-person singular simple present downregulates, present participle downregulating, simple past and past participle downregulated ) To decrease the number of cell receptors by using downregulation Antonyms [ edit] upregulate sunknowledge outlook web app