WebGrapeseed supplements contain flavonoids that reduce expression of IL-6 and partially inhibit NFκB translocation to the nucleus in some cell types . Several investigators have reported a reduction or delay of prostate tumor incidence when animals were fed grapeseed extract, resveratrol, or proanthocyanidins (19, 52, 56–58). WebFeb 20, 2004 · We investigated the in vivo efficacy of grape seed extract (GSE, patented as Traconol) against prostate cancer (PCA) and associated molecular events. Athymic nude mice were implanted with hormone-refractory human prostate carcinoma DU145 cells and fed with 100 and 200 mg/kg/day (5 days/week) doses of GSE for 7 weeks.
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