Phosphoamidit
WebFeb 1, 1998 · Rate of phosphoramidite coupling with DCI activation. All experiments were conducted under the same reaction conditions. Phosphoramidite (0.01 mmol), 2′,3′-O-isopropylidine uridine (0.011 mmol) and activator (0.08 mmol) were dissolved in CD 3 CN (0.7 ml) and the reaction rate was followed by 31 P NMR using D 3 PO 4 as an external … WebThe reaction of 2'-deoxynucleoside phosphoramidites with water is an important degradation reaction that limits the lifetimes of reagents used for chemical deoxyoligonucleotide synthesis. The hydrolysis of nucleoside phosphoramidites in solution has therefore been investigated. The degree of degrada …
Phosphoamidit
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Web2'-MOE-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methoxy-ethyl (MOE) modifications display nuclease resistance, fewer off-target effects, and... WebApr 13, 2024 · TAMRA 5’标记的寡核苷酸通常用于定量PCR和片段分析（例如，用于微卫星标记分析），因为可用的设备经常有TAMRA的检测通道。. TAMRA染料在铵和空间无位阻伯胺存在下不稳定，因此强烈建议遵循特定条件进行标记寡核苷酸脱保护。. 其他相关产品：. dU Phosphoramidite ...
Nucleoside phosphoramidites are relatively stable compounds with a prolonged shelf-life when stored as powders under anhydrous conditions in the absence of air at temperatures below 4 °C. The amidites withstand mild basic conditions. In contrast, in the presence of even mild acids, phosphoramidites perish almost instantaneously. The phosphoramidites are relatively stable to hydrolysis unde…
WebPhosphoramidites, first described in 1981, are modified nucleosides, which allow for the addition of new base sequences to the DNA strand in an extremely simple and unusually … WebThermo Scientific TheraPure®phosphoramidites are designed for oligonucleotide manufacturers requiring highly defined impurity profiles and strictly controlled processes.
WebThe Rh/BINAPa and ZSM-35(10) co-catalyzed tandem hydroformylation-acetalization of olefins has been developed. A series of olefins with various alcohols performed well in the process, affording the corresponding acetals with high regioselectivities (l/b ≥ 30.5) and excellent catalytic activities (TO …
WebThe Rh/BINAPa and ZSM-35(10) co-catalyzed tandem hydroformylation-acetalization of olefins has been developed. A series of olefins with various alcohols performed well in … t shirt rich and royalWebBuy [iBu dG Beta-Cyanoethyl Phosphoramidite] - CAS [93183-15-4] from USP tshirtriches teflon padsWebThermo Scientific modified nucleoside N 6 -Me-dA, N 4 -Ethyl-dC, and 8-oxo-dG phosphoramidites are used in specialty applications requiring high quality and performance. Modified phosphoramidites are used to synthesize oligonucleotides with base modifications that can alter the stability and melting point of duplexes. Order 8-oxo-dG CEP tshirt richesWebPhosphoramidites The addition of primary amine groups to oligonucleotides are utilized to attach a variety of modifiers (eg. NHS ester fluors) or the attachment to a solid surface. Choose from either 5′-Aminohexyl Linker or … philosophy\\u0027s 9xA phosphoramidite (RO)2PNR2 is a monoamide of a phosphite diester. The key feature of phosphoramidites is their markedly high reactivity towards nucleophiles catalyzed by weak acids e.c., triethylammonium chloride or 1H-tetrazole. In these reactions, the incoming nucleophile replaces the NR2 moiety. See more Nucleoside phosphoramidites Phosphoramidites derived from protected nucleosides are referred to as nucleoside phosphoramidites and are widely used in chemical synthesis of DNA, RNA, and other nucleic acids … See more • Phosphoramidate See more philosophy\u0027s aWeb2-Cyanoethyl N,N-diisopropylchlorophosphoramidite Cl 13.5-15.5 % Synonym (s): Chloro (diisopropylamino)-β-cyanoethoxyphosphine Linear Formula: [ (CH3)2CH]2NP (Cl)OCH2CH2CN CAS Number: 89992-70-1 Molecular Weight: 236.68 Beilstein: 3588525 MDL number: MFCD00011544 PubChem Substance ID: 24858245 NACRES: NA.22 philosophy\u0027s a1WebLNA Phosphoramidites with standard protecting groups are available with four different nucleobases: Thymine (T), 5-methyl-Cytosine (mC), Adenine (A) and Guanine (G). LNA Phosphoramidites enable synthesis of LNA-containing oligonucleotides by standard phosphoramidite chemistry, using slightly modified protocols. philosophy\\u0027s a