Strictosidine synthase-like
WebJun 29, 2024 · The enzyme strictosidine synthase (STR, EC: 4.3.3.2) plays a key role in the biosynthetic pathway of terpenoid indole alkaloid (TIA). It catalyzes the condensation of the tryptamine and ... WebAug 1, 2024 · Strictosidine synthase, an indispensable enzyme involved in the biosynthesis of terpenoid indole and β-carboline alkaloids CAO Ning, WANG Chang-Hong* The MOE …
Strictosidine synthase-like
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WebMar 26, 2024 · Strictosidine synthase, an indispensable enzyme involved in the biosynthesis of terpenoid indole and β-carboline alkaloids -carboline alkaloids CAO Ning , WANG Chang-Hong , Corresponding author: Tel: 86-21-51322511, Fax: 86-21-51322519, E-mail: [email protected]; [email protected] 1. WebSep 10, 2024 · Strictosidine biosynthesis was successfully reconstituted, with the best yields obtained by the co-expression of 14 enzymes, of which a major latex protein-like enzyme (MLPL) from Nepeta...
WebMar 1, 2002 · Protein STRICTOSIDINE SYNTHASE-LIKE 3 Gene SSL3 Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 390 Protein existence Evidence at transcript level Annotation score 2/5 Entry Feature viewer Publications External links History BLAST Download Add Add a publication Entry … WebHere, the very recent work on strictosidine synthase (STR) will be discussed as an illustrative case. 47 STR catalyzes the Pictet−Spengler (PS) condensation between tryptamine and secologanin to ...
Strictosidine synthase (EC 4.3.3.2) is an enzyme in alkaloid biosynthesis that catalyses the condensation of tryptamine with secologanin to form strictosidine in a formal Pictet–Spengler reaction: 3-α(S)-strictosidine + H2O = tryptamine + secologanin Since the condensation of tryptamine and secologanin is the first committed step in alkaloid syn… WebProtein STRICTOSIDINE SYNTHASE-LIKE 6 1 publication Short names AtSSL6 1 publication Gene names Name SSL6 1 publication ORF names F26O13.80 Imported Ordered locus names At3g51440 Imported Organism names Organism Arabidopsis thaliana (Mouse-ear cress) Imported Taxonomic identifier 3702 NCBI Taxonomic lineage
WebJan 1, 2008 · Strictosidine synthase, ... (Figure 2), we propose that the newly deprotonated Glu309 (like acetate in the solution reaction) could also catalyze the rate-limiting deprotonation step (Figure 1, step 5; Figure 2). Strictosidine synthase catalyzes iminium formation, which can be rate limiting in solution. The enzyme acts as a scaffold to …
WebStrictosidine synthase (STR) is a key enzyme in the biosynthesis of terpenoid indole alkaloids. This class of secondary metabolites harbours several pharmaceutically important compounds used, among other applications, in cancer treatment. fun place to go with kidsWebThe strictosidine synthase-like (SSL) subgroup, the primary focus of this paper, currently includes three experimentally characterized SSs from R. serpentina. 8, C. roseus. 9, and O. pumila. 10. along with a much larger group of ~500 SSL sequences for which the reaction specificity has not been experimentally identified but that have been ... fun plastic food storage containersWebSSL2 strictosidine synthase-like 2 [ (thale cress)] Gene ID: 818728, updated on 10-Apr-2024. Summary. Although this enzyme is predicted to encode a strictosidine synthase (SS), it … fun places to walk in atlantaWebGene ID: 107790267, updated on 2-Jun-2024. Summary Other designations. protein STRICTOSIDINE SYNTHASE-LIKE 10-like, strictosidine synthase-like protein, strictosidine synthase-like protein github actions upload to azure blobWebSSL3, STRICTOSIDINE SYNTHASE-LIKE 3 Description Although this enzyme is predicted to encode a strictosidine synthase (SS), it lacks a conserved catalytic glutamate residue found in active SS enzymes and it is not expected to have SS activity. Map Detail Image Center on AT1G08470 Full-screen view Annotations Sequence github actions upload artifactWebDespite these differences, comparison of conserved catalytic features of the arylesterase-like and SGL enzymes with the SSs identified similar structural and mechanistic attributes between the hydrolytic reactions catalyzed by the former and the condensation reaction catalyzed by SS. fun plastic containers for slimeWebStrictosidine synthase protein is one of the key enzymes involved in the biosynthesis of plant alkaloids. To date, no information on strictosidine synthase sequences of Papaver somniferum has been recorded in various databases. Therefore, the aim of this study was to isolate the complete ORF sequence of strictosidine gene, bioinformatics analysis of this … github actions valet